Vivamer - Polymers for Life 2005-01-20T08:26:14Z tag:www.vivamer.com,2005:/1 Movable Type Copyright (c) 2005, vivamer Revolutionary Drug Delivery and Imaging 2005-01-20T08:26:14Z 2005-01-20T08:26:14+00:00 tag:www.cheng.cam.ac.uk,2005:/research/groups/biosci/vivamer//1.3 2005-01-20T08:26:14Z Vivamer creates novel drugs based on its unique responsive biopolymer chemistry platform. Spun out of Department of Chemical Engineering, University of Cambridge, the company was established in 2002 to commercialize technology developed by founders Professor Nigel Slater and Dr Mark... vivamer About Vivamer Vivamer creates novel drugs based on its unique responsive biopolymer chemistry platform. Spun out of Department of Chemical Engineering, University of Cambridge, the company was established in 2002 to commercialize technology developed by founders Professor Nigel Slater and Dr Mark Eccleston.

]]> Award for CEO 2004-07-12T16:55:58Z 2004-07-12T17:55:58+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.40 2004-07-12T16:55:58Z Professor Nigel Slater, Vivamer's CEO, has been elected as a Fellow of the Royal Academy of Engineering (FREng), in recognition of his academic and commercial achievements.... vivamer News Professor Nigel Slater, Vivamer's CEO, has been elected as a Fellow of the Royal Academy of Engineering (FREng), in recognition of his academic and commercial achievements.


]]> Drug Delivery Collaborations 2004-06-26T07:30:49Z 2004-06-26T08:30:49+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.38 2004-06-26T07:30:49Z Vivamer's research is currently focused on the exemplification of the responsive polymer chemistry as a drug delivery system for solid tumors. The company is initially using the established anti-cancer drug, doxorubicin, to demonstrate the capabilities of the system. This will... vivamer Collaborations Vivamer's research is currently focused on the exemplification of the responsive polymer chemistry as a drug delivery system for solid tumors. The company is initially using the established anti-cancer drug, doxorubicin, to demonstrate the capabilities of the system. This will enable the company to provide potential partners with quantitative benefits of using a responsive drug delivery system over a non-formulated drug.

Vivamer is interested in exploring potential partnerships with biotechs or pharmaceutical companies to co-develop the novel polymer-encapsulated doxorubicin. Vivamer is also open to the possibility of collaborations with drug delivery specialists that wish to broaden their portfolio of product offerings.

In future, Vivamer intends to develop drug/delivery products in collaboration with pharmaceutical companies that provide the active therapeutic compound. These projects will be structured to include costs of research, milestone payments and royalties on product sales. Pharmaceutical partners will be granted a sub-license for specific named delivery applications.

]]> Bio2004 2004-06-10T09:51:59Z 2004-06-10T10:51:59+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.35 2004-06-10T09:51:59Z Vivamer participated in the BIO 2004 Annual International Convention in San Francisco on June 6-9th 2004. The company was represented by the Chief Commercial Officer, Mr John Rountree.... vivamer News Vivamer participated in the BIO 2004 Annual International Convention in San Francisco on June 6-9th 2004. The company was represented by the Chief Commercial Officer, Mr John Rountree.

]]> Vivamer' presence at this meeting was related to its interest in meeting potential collaboration partners of two types:
  • Pharmaceutical companies wishing to co-develop novel drugs that are based on thier own active molecule(s) and Vivamer's unique polymer drug delivery system

  • Drug delivery companies wishing to complement their own drug delivery capabilities with polymer chemistry expertise

]]> Responsive Polymers 2004-05-24T16:34:08Z 2004-05-24T17:34:08+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.8 2004-05-24T16:34:08Z Vivamer has developed a range of polymer backbones that have been designed to react to environmental triggers, e.g. pH change, light or temperature. The responsive polymers act as a chemical switch, activating or releasing a payload agent in response to... vivamer Technology Vivamer has developed a range of polymer backbones that have been designed to react to environmental triggers, e.g. pH change, light or temperature. The responsive polymers act as a chemical switch, activating or releasing a payload agent in response to the environmental stimulus. Polymer chemistries have been synthesized that will react within a series of narrowly defined pH windows, or specific wavelengths of light. The switching event is achieved by causing the polymers to change their conformation.

The responsive polymers can be deployed in a range of polymer formats, providing Vivamer's partners with a number of product design options, including soluble conjugates, encapsulated nano-particles, responsive films and implants.

]]> Molecular Animation 2004-05-23T09:35:57Z 2004-05-23T10:35:57+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.21 2004-05-23T09:35:57Z vivamer Technology hypercoiling effect ]]> Nuclear Targeting 2004-05-22T09:52:10Z 2004-05-22T10:52:10+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.27 2004-05-22T09:52:10Z vivamer Technology Cartoon Showing Nuclear Targeting ]]> Drug Delivery to Solid Tumours 2004-05-21T09:42:52Z 2004-05-21T10:42:52+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.25 2004-05-21T09:42:52Z Polymer conjugate or encapsulated nanoparticle Accumulation enhanced by leaky vasculature Polymer response triggered by lower pH of Tumour... vivamer Technology Enhanced Permeation and Retention Effect

  • Polymer conjugate or encapsulated nanoparticle
  • Accumulation enhanced by leaky vasculature
  • Polymer response triggered by lower pH of Tumour
]]> Imaging of Solid Tumours 2004-05-20T09:50:46Z 2004-05-20T10:50:46+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.26 2004-05-20T09:50:46Z Unmet Need Conclusive diagnosis Management of treatment MRI Responsive agent activated by pH Fluorescence/FRET Low cost Responsive agent activated by pH... vivamer Technology
  • Unmet Need
    • Conclusive diagnosis
    • Management of treatment
  • MRI
    • Responsive agent activated by pH
  • Fluorescence/FRET
    • Low cost
    • Responsive agent activated by pH
    ]]>     Functional Cardiac Imaging 2004-05-19T10:00:16Z 2004-05-19T11:00:16+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.28 2004-05-19T10:00:16Z Vivamer’s responsive polymer technology can be used to develop imaging agents with: Enhanced circulatory half life (days) Reduced interstitial leakage (enhanced signal to noise) Enhanced intrinsic brightness Multi labelled polymers for ultra brightness and reduced first pass dilution Dual labels... vivamer Technology Vivamer’s responsive polymer technology can be used to develop imaging agents with:
    • Enhanced circulatory half life (days)

    • Reduced interstitial leakage (enhanced signal to noise)

    • Enhanced intrinsic brightness

    • Multi labelled polymers for ultra brightness and reduced first pass dilution

    • Dual labels MRI, Fluorescence, CT contrast

    • Site specific switching capability

      • pH

      • Temperature

      • Oxygen tension

      • Plaque targeting capability

    ]]>     Nuclear Targeting Images 2004-05-14T13:22:06Z 2004-05-14T14:22:06+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.34 2004-05-14T13:22:06Z vivamer Nuclear Targeting Visualised  Nuclear Targeting Visualised in Mitotic Cells

    Images Showing Nuclear Targeting Visualised in Mitotic Cells

    ]]>     Smart Encapsulation 2004-05-10T10:06:40Z 2004-05-10T11:06:40+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.31 2004-05-10T10:06:40Z Tuneable pH of dissolution Tuneable rate of dissolution Self plasticising films Functional films Surfactant, Bleach Conditioner, Rinse agent, Antimicrobial, Embedded reagents.... vivamer release
    • Tuneable pH of dissolution

    • Tuneable rate of dissolution

    • Self plasticising films

    • Functional films

      Surfactant, Bleach Conditioner, Rinse agent, Antimicrobial, Embedded reagents.

    release

    ]]>     Household Care Application 2004-05-10T10:04:21Z 2004-05-10T11:04:21+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.30 2004-05-10T10:04:21Z vivamer vivamer polymers in your washing machine

    ]]>     Enhanced Permeation and Retention 2004-05-10T09:41:33Z 2004-05-10T10:41:33+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.24 2004-05-10T09:41:33Z vivamer Enhanced Permeation and Retention Effect

    ]]>     Oxygen responsive gelling 2004-05-10T09:39:09Z 2004-05-10T10:39:09+00:00 tag:www.cheng.cam.ac.uk,2004:/research/groups/biosci/vivamer//1.33 2004-05-10T09:39:09Z Mussels do it ... So do we ...... vivamer Mussels do it ...


    mussel holding a brick


    So do we ...

    ]]>